Human FSHβ subunit gene is highly conserved

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Human FSHβ subunit gene is highly conserved

FSH is a pituitary gonadotropin that along with LH plays a key role in the regulation of gonadal function. The gonadotropic hormones are composed of two subunits, the common subunit and the hormone-specific subunit, which determines the binding to specific receptors and induction of biological response. Unlike the LH gene, shown in earlier studies to harbour several amino acid-altering polymorp...

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Identifying Highly Conserved and Highly Differentiated Gene Ontology Categories in Human Populations

Detecting and interpreting certain system-level characteristics associated with human population genetic differences is a challenge for human geneticists. In this study, we conducted a population genetic study using the HapMap genotype data to identify certain special Gene Ontology (GO) categories associated with high/low genetic difference among 11 Hapmap populations. Initially, the genetic di...

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ژورنال

عنوان ژورنال: MHR: Basic science of reproductive medicine

سال: 2005

ISSN: 1460-2407,1360-9947

DOI: 10.1093/molehr/gah198